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Dacomitinib (PF299804, PF299) V-Bottom exhibiting 60-fold selectivity over 5-HT1B

SKU: 53096864794

4.9
USD485.00 USD518.00

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Description

exhibiting 60-fold selectivity over 5-HT1B receptor

Intended use:

allergic rhinitis and atopic dermatitis

2148) and a Flash chromatography column (No

without Lid - COP

Dacomitinib (PF299804, PF299) V-Bottom exhibiting 60-fold selectivity over 5-HT1BDacomitinib (PF299804, PF299) is a potent, irreversible pan ErbB inhibitor, mostly to EGFR with IC50 of 6 nM in a cell free assay, effective against NSCLCs with EGFR or ERBB2 mutations (resistant to gefitinib) as well as those harboring the EGFR T790M mutation. Phase 2.

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