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The strain in DBCO’s cyclooctyne ring drives the reaction forward by releasing energy when it transitions to the triazole product
is a key reagent in click chemistry
187 SMILES OC(=O)CC1=CNC2=C1C=CC=C2 Purity (HPLC) >= 95% Physical Appearance White solid Solubility DMSO
forming a triazole ring and often used in drug development
199 Purity (HPLC) >= 95% Solubility DMSO
Azide-Hexanoyl-Val-Ala-PAB(m-PEG8) Size:10mg The strain in DBCO’s cyclooctyneSOLU KNEX cleavable linker features a Val Ala dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine containing groups, or polysarcosine (PSAR), to enhance aqueous solubility. Solubility and physicochemical properties can be finely tuned through selection
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