Fmoc-Val-Cit-PAB amine-amine Product Name Thalidomide-5'-O-PEG3-C2-azide Synonyms CAS

Product Name Thalidomide-5'-O-PEG3-C2-azide Synonyms CAS Number n/a Related CAS Molecular Formula C21H25N5O8 Molecular Weight 475

The red-fluorescent 5-TAMRA alkyne is an excellent azide-reactive fluorescent reagent for labeling alkyne-containing biological molecules through click chemitry

616 Purity (HPLC) >= 95% Solubility DMSO

96 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCOCCOCCOCCOCCOCCOCC(O)=O)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Contains an E3 ligase ligand with alkyl linker and a terminal piperazine moiety

Fmoc-Val-Cit-PAB amine-amine Product Name Thalidomide-5'-O-PEG3-C2-azide Synonyms CASFmoc Val Cit PAB is a cleavable ADC linker featuring a ValCit dipeptide and a para aminobenzyl (PAB) spacer. The ValCit sequence is selectively cleaved by cathepsin B in lysosomes, while the para aminobenzyl (PAB) spacer supports self immolative release of the attached drug, and the Fmoc protecting group can be removed to enable further functionalization or conjugation. Product Name Fmoc Val Cit PAB Synonyms Fmoc VC PAB OH CAS Number 159858 22 7