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Azide-Propionyl-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan dbco-hexanoyl Product Name Mal-Propionyl-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4) Synonyms CAS

SKU: 67926156858

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Description

Product Name Mal-Propionyl-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4) Synonyms CAS Number Related CAS Molecular Formula C52H75N9O19 Molecular Weight 1130

366 SMILES OCCOCCCC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

5 Purity (HPLC) >= 95% Solubility DMSO

Product Name Mal-Propiony-Beta-Ala-Gly-Gly-Phe-Gly-PAB(m-PEG8) Synonyms CAS Number Related CAS Molecular Formula C50H72N8O18 Molecular Weight 1073

The red-fluorescent 5(6)-TAMRA azide is an excellent alkyne-reactive fluorescent reagent for labeling alkyne-containing biological molecules through click chemitry

Azide-Propionyl-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan dbco-hexanoyl Product Name Mal-Propionyl-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4) Synonyms CASSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures, SOLU

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