MC-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE fluorescent 42 SMILES CC(C)(C)OC(=O)NCCN1CCN(CCCN)CC1 Purity (HPLC)

42 SMILES CC(C)(C)OC(=O)NCCN1CCN(CCCN)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name DBCO-Lys(m-PEG4)-Val-Ala-PAB(m-PEG4) Synonyms CAS Number Related CAS Molecular Formula C60H85N7O16 Molecular Weight 1160

CC0651 is an E2 enzyme inhibitor

Iberdomide (CC-220) is an orally active and potent cereblon (CRBN) E3 ligase modulator (CELMoD) with an IC50 of 150

such as  MRI contrast agents

MC-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE fluorescent 42 SMILES CC(C)(C)OC(=O)NCCN1CCN(CCCN)CC1 Purity (HPLC)SOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers