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Mal-Propionyl-PEG8-Gly-Gly-Phe-Gly-PAB(m-PEG4) deuterium-labeled-amine Product Name 4-bromo-3-(methoxy-d3)-benzaldehyde Synonyms CAS

SKU: 35118147705

4.2
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Description

Product Name 4-bromo-3-(methoxy-d3)-benzaldehyde Synonyms CAS Number n/a Related CAS Molecular Formula C8H7BrO2 Molecular Weight 218

VHL-SNAP2-5C is a SNAP PROteolysis TArgeting Chimera (SNAP-PROTAC)

403 SMILES O=C1N(C2CCC(=O)NC2=O)C(=O)C2=C(NCCOCCOCC#C)C=CC=C12 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

SHP099 is a highly potent (IC50 = 0

037 Purity (HPLC) >= 95% Solubility DMSO

Mal-Propionyl-PEG8-Gly-Gly-Phe-Gly-PAB(m-PEG4) deuterium-labeled-amine Product Name 4-bromo-3-(methoxy-d3)-benzaldehyde Synonyms CASSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG8 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. Derived from established ADC linker

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