DBCO-Dap(m-PEG4)-Val-Ala-PAB-PNP Pomalidomide 275 (2024)

275 (2024)

Product Name Azide-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8) Synonyms CAS Number Related CAS Molecular Formula C53H84N10O20 Molecular Weight 1181

Product Name Lenalidomide-acetamido-O-PEG2-C2-Cl Synonyms Lenalidomide-4'-acetamido-O-PEG2-C2-Cl CAS Number n/a Related CAS Molecular Formula C21H26ClN3O7 Molecular Weight 467

376 Purity (HPLC) >= 95% Solubility DMSO

362 SMILES CC(C)(C)OC(=O)CCOCCN1CCNCC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

DBCO-Dap(m-PEG4)-Val-Ala-PAB-PNP Pomalidomide 275 (2024)SOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, a DBCO Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG,