DBCO-Dap(m-PEG4)-Gly-Gly-Phe-Gly propargyl-acetyl 584 SMILES OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)NCCCCCN=[N+]=[N-])CCN(CC(O)=O)CC1 Purity (HPLC)

584 SMILES OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)NCCCCCN=[N+]=[N-])CCN(CC(O)=O)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

NCCCCCCOC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

44 SMILES CC1=CN=C(NC(=O)CC2=CSC(NC3=NC(C)=CC=C3)=N2)S1 Purity (HPLC) >= 95% Physical Appearance White solid Solubility DMSO

Nat Commun 15

S)-AHPC-CO-PEG7-OH Synonyms CAS Number n/a Related CAS Molecular Formula C37H58N4O11S Molecular Weight 766

DBCO-Dap(m-PEG4)-Gly-Gly-Phe-Gly propargyl-acetyl 584 SMILES OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)NCCCCCN=[N+]=[N-])CCN(CC(O)=O)CC1 Purity (HPLC)SOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a DBCO Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing